Moesha je situačná komédia, sledujúca život a dobu černošskej tínedžerky Moeshy Mitchell, ktorá žije v oblasti Leimert Park v Los Angeles, štát California. Jej matka zomrela pred rokmi a Moesha sa tak musí starať o svojho otca Franka a mladšieho brata Mylesa. Keď sa učiteľka z jej školy Dee za Franka vydá, Moesha má pocit, že jej pôsobenie ohrozuje jej nová nevlastná matka. Časom sa však dve ženy v dome naučia navzájom sa vážiť a tešiť sa zo svojej prítomnosti.
Moesha má aj najlepšieho priateľa Kima, ktorý je značne bláznivý a podobá sa na jej večne hladného suseda a kamaráta Hakeema. Títo dvaja Mo podporujú počas všetkých jej ťažkostí. Ďalšou blízkou Moeshinou dôverníčkou je Andelle, majiteľka miestneho obchodu. Práve ona poskytuje v prípade potreby mladému dievčaťu rady a múdrosti súvisiace s peripetiami dospievania.
Hrají: Brandy Norwood, William Allen Young, Marcus T. Paulk, Lamont Bentley, Shar Jackson, Sheryl Lee Ralph, Yvette Wilson, Dru Mouser, Usher, .....Bernie Mac, Fredro Starr, Ray J, Dante Basco, Shad Moss, Michael Peña, Gabrielle Union, Robert Guillaume, J. August Richards, Dorian Gregory, Flex Alexander, Octavia Spencer, Malinda Williams, Jamal Mixon, Angie Stone, Jason George, Jazsmin Lewis, Damon Standifer, Tommy 'Tiny' Lister, Golden Brooks, Mo'Nique, Angell Conwell, Don Franklin, Victoria Dillard, Danielle Nicolet, Antwon Tanner, Jon Huertas, Courtney Ford, Bree Turner, Richard Gant, Adrian R'Mante, Maureen McCormick, Cirroc Lofton, Kristy Wu, Kelvin Brown, Chico Benymon, Datari Turner, Lawrence Hilton-Jacobs, Mara Brock Akil, Angelo Pagán, Walter Jones, T.K. Carter, Jennifer Elise Cox, Andray Johnson, Sean Moran, Retta, Aaron Lustig, Carlos Mencia, Orlando Brown, Brent Jennings, Darius McCrary, Brandon Quintin Adams, Anthony C. Hall, Samantha Esteban, Harold Sylvester, Karim Prince, Demetrius Navarro, Brook Kerr, Dorien Wilson, John Prosky, Amy Gross, Kellita Smith, Wesley Jonathan, Billy 'Sly' Williams, Estelle Harris, Doug Cox, Selwyn Ward, Sydney Bennett, Lawrence Mandley, Dale Godboldo, Hal Williams, Richard Whiten, Ricky Harris, Lynn Hamilton, Michael Ralph, Russell Simmons, Earl Billings, Gonzalo Menendez, Christian Coleman, Henry G. Sanders, Ashley Monique Clark, Deborah Lacey, Jermaine 'Huggy' Hopkins, Scott Hamm, Jorge-Luis Pallo, Karimah Westbrook, Julius Tennon, Jo Marie Payton, Ja'net DuBois, Wren T. Brown, Bee-Be Smith, Kobe Bryant, Danny Mora, Ptosha Storey, Ben Watkins, Lee Chamberlin, MC Lyte, Chuti Tiu, Lisa Leslie, Olivia Brown, Marissa Jaret Winokur, Denise Dowse, Vaughn Armstrong, Chrystee Pharris, Montrose Hagins, Trae Ireland, Toby Smith, Nancy Wilson, Dennis Neal, Joi Starr, Chaz Lamar Shepherd, Kenny Blank, Tamara LaSeon Bass, Julius Carry, Clyde R. Jones, Nigél Thatch, Nikkole Salter, Lahmard J. Tate, Alexis Fields, Nick Spano, Catherine Dao, Alex Thomas, Francesca P. Roberts, Kellie Shanygne Williams, Kevin Dunigan, Jenna von Oÿ, Iona Morris, Granville Ames, Vivian Bonnell, Arvie Lowe Jr., Kente Scott, David Michael, Wanda Acuna, Jacquelyn Houston, Quincy Le Near, Nick DeMauro, Vince Carter, Erik Alexander Gavica, Vicellous Reon Shannon, Bo Jackson, Jamie Foxx, Andrew Keegan, Judy Kain, Curtis Baldwin, Damara Reilly, Mailon Rivera, Marsha Warfield, Pat Millicano, Richard Penn, WC, Countess Vaughn, Ken Lawson, Maia Campbell, Merlin Santana, Curtis Williams, Anthony Johnson, Shawn Harrison, Shania Accius, Nathan Morris, Michael McCary, Wanya Morris, Shawn Stockman, Johnny Gill, Jesika Reynolds, Sonia Iris Lozada, J. Anthony Brown, Emmanuel Lewis, Daniel Murillo, Braeden Marcott, Crystal Scales, Karen Hartman
Režie: Henry Chan, Ken Whittingham, Stan Lathan, Ted Lange, William Allen Young, Tony Singletary, Erma Elzy, Shirley Jo Finney, Shirley Jo Finney
Tvůrci: Ralph Farquhar, Sara Finney-Johnson, Vida Spears
Scénář: Mara Brock Akil, Norman Vance Jr., Ilunga Adell, Jacque Edmonds, Warren Hutcherson, Eric Monte, Ralph Farquhar, Sara Finney-Johnson, Vida Spears, .....Felicia D. Henderson, Calvin Brown Jr.
Producenti: Leo Clarke, W.E. Baker, James Tripp-Haith
Hudba: Kurt Farquhar
Kamera: Julius Metoyer, Donald A. Morgan
Střih: Jim McQueen, Brian Schnuckel
Scénografie: Michele Sefman, Richard Improta, Cheryle Grace
Kostýmy a make-up: Louisa V. Anthony, Michelle Cole, Warren Lewis, Nanrose Buchman, Eddie M. Barron, Yolanda Braddy, Sheila Evers, Debra Y. Brown, Debra Denson, .....Phyllis Williams, Kim Addrisi, Debbie Pierce, Frank Fontaine, LaLette Littlejohn, Carol McCoo
Zvuk: Tamara Johnson, Rick Himot, Ross Davis, Dana Mark McClure, Charlie McDaniel, Peter Damski, Laura King, Russell Williams II, Russell Williams II
